Consuming yellow pea fiber reduces voluntary energy intake and body fat in overweight/obese adults in a 12-week randomized controlled trial

Published:January 11, 2016DOI:https://doi.org/10.1016/j.clnu.2015.12.016

      Summary

      Background & aims

      The purpose of this randomized, double-blind, placebo-controlled study was to assess the effects of yellow pea fiber intake on body composition and metabolic markers in overweight/obese adults.

      Methods

      Participants (9 M/41 F; age 44 ± 15 y, BMI 32.9 ± 5.9 kg/m2) received isocaloric doses of placebo (PL) or pea fiber (PF; 15 g/d) wafers for 12 weeks. Outcome measures included changes in anthropometrics, body composition (DXA), oral glucose tolerance test (OGTT), food intake (ad libitum lunch buffet), and biochemical indices.

      Results

      The PF group lost 0.87 ± 0.37 kg of body weight, primarily due to body fat (−0.74 ± 0.26 kg), whereas PL subjects gained 0.40 ± 0.39 kg of weight over the 12 weeks (P = 0.022). The PF group consumed 16% less energy at the follow-up lunch buffet (P = 0.026), whereas the PL group did not change. During the OGTT, glucose area under the curve (AUC) was lower in PF subjects at follow-up (P = 0.029); insulin increased in both groups over time (P = 0.008), but more so in the PL group (38% higher AUC vs. 10% higher in the PF group). There were no differences in gut microbiota between groups.

      Conclusions

      In the absence of other lifestyle changes, incorporating 15 g/day yellow pea fiber may yield small but significant metabolic benefits and aid in obesity management.
      Clinical Trial Registry: ClinicalTrials.gov NCT01719900.

      Keywords

      Abbreviations:

      DXA (dual X-ray absorptiometry), tAUC (total area under the curve), OGTT (oral glucose tolerance test), PF (pea fiber), PL (placebo), VAS (visual analog scales)
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      References

        • Kristensen M.
        • Jensen M.G.
        Dietary fibres in the regulation of appetite and food intake. Importance of viscosity.
        Appetite. 2011; 56: 65-70
        • Dewulf E.M.
        • Cani P.D.
        • Claus S.P.
        • Fuentes S.
        • Puylaert P.G.B.
        • Neyrinck A.M.
        • et al.
        Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women.
        Gut. 2013; 62: 1112-1121
        • Roberfroid M.
        • Gibson G.R.
        • Hoyles L.
        • McCartney A.L.
        • Rastall R.
        • Rowland I.
        • et al.
        Prebiotic effects: metabolic and health benefits.
        Br J Nutr. 2010; 104: S1-S63
        • Health Canada
        Do Canadian adults meet their nutrient requirements through food intake alone?.
        2012 (Available at:)
        • Sosulski F.W.
        • Wu K.K.
        High-fiber breads containing field pea hulls, wheat, corn, and wild oat brans.
        Cereal Chem. 1983; 65 (Available at:): 186-191
        • Whitlock K.A.
        • Kozicky L.
        • Jin A.
        • Yee H.
        • Ha C.
        • Morris J.
        • et al.
        Assessment of the mechanisms exerting glucose-lowering effects of dried peas in glucose-intolerant rats.
        Br J Nutr. 2012; 108: S91-S102
        • Marinangeli C.P.F.
        • Krause D.
        • Harding S.V.
        • Rideout T.C.
        • Zhu F.
        • Jones P.J.H.
        Whole and fractionated yellow pea flours modulate insulin, glucose, oxygen consumption, and the caecal microbiome in Golden Syrian hamsters.
        Appl Physiol Nutr Metab. 2011; 36: 811-820
        • Eslinger A.J.
        • Eller L.K.
        • Reimer R.A.
        Yellow pea fiber improves glycemia and reduces Clostridium leptum in diet-induced obese rats.
        Nutr Res. 2014; 34: 714-722
        • Marinangeli C.P.F.
        • Jones P.J.H.
        Whole and fractionated yellow pea flours reduce fasting insulin and insulin resistance in hypercholesterolaemic and overweight human subjects.
        Br J Nutr. 2011; 105: 110-117
        • Lambert J.E.
        • Parnell J.A.
        • Han J.
        • Sturzenegger T.
        • Paul H.A.
        • Vogel H.J.
        • et al.
        Evaluation of yellow pea fibre supplementation on weight loss and the gut microbiota: a randomized controlled trial.
        BMC Gastroenterol. 2014; 14: 69
        • Parnell J.A.
        • Reimer R.A.
        Weight loss during oligofructose supplementation is associated with decreased ghrelin and increased peptide YY in overweight and obese adults.
        Am J Clin Nutr. 2009; 89: 1751-1759
        • Stubbs R.J.
        • Hughes D.A.
        • Johnstone A.M.
        • Rowley E.
        • Reid C.
        • Elia M.
        • et al.
        The use of visual analogue scales to assess motivation to eat in human subjects: a review of their reliability and validity with an evaluation of new hand-held computerized systems for temporal tracking of appetite ratings.
        Br J Nutr. 2000; 84: 405-415
        • Gregersen N.T.
        • Flint A.
        • Bitz C.
        • Blundell J.E.
        • Raben A.
        • Astrup A.
        Reproducibility and power of ad libitum energy intake assessed by repeated single meals.
        Am J Clin Nutr. 2008; 87: 1277-1281
        • Bomhof M.R.
        • Saha D.C.
        • Reid D.T.
        • Paul H.A.
        • Reimer R.A.
        Combined effects of oligofructose and Bifidobacterium animalis on gut microbiota and glycemia in obese rats.
        Obes Silver Spring. 2014; 22: 763-771
        • Parnell J.A.
        • Reimer R.A.
        Prebiotic fibres dose-dependently increase satiety hormones and alter Bacteroidetes and Firmicutes in lean and obese JCR: LA-cp rats.
        Br J Nutr. 2012; 107: 601-613
        • Dubois C.
        • Cara L.
        • Armand M.
        • Borel P.
        • Senft M.
        • Portugal H.
        • et al.
        Effects of pea and soybean fibre on postprandial lipaemia and lipoproteins in healthy adults.
        Eur J Clin Nutr. 1993; 47: 508-520
        • Hamberg O.
        • Rumessen J.J.
        • Gudmand-Høyer E.
        Blood glucose response to pea fiber: comparisons with sugar beet fiber and wheat bran.
        Am J Clin Nutr. 1989; 50: 324-328
        • Marinangeli C.P.F.
        • Kassis A.N.
        • Jones P.J.H.
        Glycemic responses and sensory characteristics of whole yellow pea flour added to novel functional foods.
        J Food Sci. 2009; 74: S385-S389
        • Sandström B.
        • Hansen L.T.
        • Sørensen A.
        Pea fiber lowers fasting and postprandial blood triglyceride concentrations in humans.
        J Nutr. 1994; 124: 2386-2396
        • Pyra K.A.
        • Saha D.C.
        • Reimer R.A.
        Prebiotic fiber increases hepatic acetyl CoA carboxylase phosphorylation and suppresses glucose-dependent insulinotropic polypeptide secretion more effectively when used with metformin in obese rats.
        J Nutr. 2012; 142: 213-220
        • Reimer R.A.
        • Maurer A.D.
        • Eller L.K.
        • Hallam M.C.
        • Shaykhutdinov R.
        • Vogel H.J.
        • et al.
        Satiety hormone and metabolomic response to an intermittent high energy diet differs in rats consuming long-term diets high in protein or prebiotic fiber.
        J Proteome Res. 2012; 11: 4065-4074
        • Islam A.
        • Civitarese A.E.
        • Hesslink R.L.
        • Gallaher D.D.
        Viscous dietary fiber reduces adiposity and plasma leptin and increases muscle expression of fat oxidation genes in rats.
        Obes Silver Spring. 2012; 20: 349-355
        • Mollard R.C.
        • Luhovyy B.L.
        • Smith C.
        • Anderson G.H.
        Acute effects of pea protein and hull fibre alone and combined on blood glucose, appetite, and food intake in healthy young men – a randomized crossover trial.
        Appl Physiol Nutr Metab. 2014; 39: 1360-1365
        • Smith C.E.
        • Mollard R.C.
        • Luhovyy B.L.
        • Anderson G.H.
        The effect of yellow pea protein and fibre on short-term food intake, subjective appetite and glycaemic response in healthy young men.
        Br J Nutr. 2012; 108: S74-S80
        • Westerterp K.R.
        • Goris A.H.
        Validity of the assessment of dietary intake: problems of misreporting.
        Curr Opin Clin Nutr Metab Care. 2002; 5: 489-493
        • Ebbeling C.B.
        • Swain J.F.
        • Feldman H.A.
        • Wong W.W.
        • Hachey D.L.
        • Garcia-Lago E.
        • et al.
        Effects of dietary composition on energy expenditure during weight -loss maintenance.
        JAMA. 2012; 307: 2627-2634
        • Maccaferri S.
        • Klinder A.
        • Cacciatore S.
        • Chitarrari R.
        • Honda H.
        • Luchinat C.
        • et al.
        In vitro fermentation of potential prebiotic flours from natural sources: impact on the human colonic microbiota and metabolome.
        Mol Nutr Food Res. 2012; 56: 1342-1352
        • Biesiekierski J.R.
        • Rosella O.
        • Rose R.
        • Liels K.
        • Barrett J.S.
        • Shepherd S.J.
        • et al.
        Quantification of fructans, galacto-oligosacharides and other short-chain carbohydrates in processed grains and cereals.
        J Hum Nutr Diet. 2011; 24: 154-176
        • Da S.
        • Queiroz-Monici K.
        • Costa G.E.
        • da Silva N.
        • Reis S.M.P.M.
        • de Oliveira A.C.
        Bifidogenic effect of dietary fiber and resistant starch from leguminous on the intestinal microbiota of rats.
        Nutrition. 2005; 21: 602-608
        • Chen H.
        • Mao X.
        • He J.
        • Yu B.
        • Huang Z.
        • Yu J.
        • et al.
        Dietary fibre affects intestinal mucosal barrier function and regulates intestinal bacteria in weaning piglets.
        Br J Nutr. 2013; 110: 1837-1848
        • Eckburg P.B.
        • Bik E.M.
        • Bernstein C.N.
        • Purdom E.
        • Dethlefsen L.
        • Sargent M.
        • et al.
        Diversity of the human intestinal microbial flora.
        Science. 2005; 308: 1635-1638
        • Turnbaugh P.J.
        • Hamady M.
        • Yatsunenko T.
        • Cantarel B.L.
        • Duncan A.
        • Ley R.E.
        • et al.
        A core gut microbiome in obese and lean twins.
        Nature. 2009; 457 (Nature Publishing Group): 480-484