Methodological issues on açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study

Published:December 04, 2021DOI:https://doi.org/10.1016/j.clnu.2021.12.001
      I was interested to read the paper authored by de Liz et al. [
      • de Liz S.
      • Cardoso A.L.
      • Copetti C.L.
      • de Fragas Hinnig P.
      • Vieira F.G.
      • da Silva E.L.
      • et al.
      Açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study.
      ] which is published in the Journal of Clinical Nutrition in Dec 2020. The authors aimed that the a positive impact of regular consumption of açaí and juçara juices on the HDL-c levels, as well as on the antioxidant enzyme activities, which may contribute to cardiovascular health with a cross-over study. Although the results of the study are very interesting, however, it seems that several statistical and methodological issues should be considered when interpreting the results.
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